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 Leadership
 Senior Management
 Board of Directors
Michael Schmertzler
Harvey Berger, M.D.
Axel Bolte
Søren Carlsen, Ph.D.
Carl Goldfischer, M.D.
Allan Jacobson, Ph.D.
Michael Kranda
Stuart W. Peltz, Ph.D.
David P. Southwell
 Scientific Advisory Board
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 Working at PTC

Designee of Credit Suisse First Boston Equity Partners
Michael Schmertzler has served as a member of PTC's board of directors since August 2001 and as Chairman of the Board since November 2004. Since 2001, Mr. Schmertzler has been a Managing Director of Aries Advisors, LLC, the sub-advisor to Credit Suisse First Boston Equity Partners, L.P., a private equity fund, and the Chair of the investment committee. From 1997 to 2001, Mr. Schmertzler was Co-Head of United States and Canadian Private Equity at Credit Suisse First Boston, an investment banking company. Prior to 1997, Mr. Schmertzler held various management positions with Morgan Stanley and its affiliates, including President of Morgan Stanley Leveraged Capital Funds and Managing Director, and was Managing Director and Chief Financial Officer of Lehman Brothers Kuhn Loeb, an investment banking firm. Mr. Schmertzler is also a director of Cytokinetics, Incorporated and since 1978, has been an Adjunct Professor at Yale University. Mr. Schmertzler received a B.A. from Yale College in Molecular Biophysics and Biochemistry, History and City Planning and an M.B.A. from the Harvard Business School.